Product: NAD+ (1000mg)

SKU: # 0015 Category:

NAD+ (1000mg)

NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in all living cells, involved in over 500 enzymatic reactions. Laboratory research examines its role in redox metabolism, sirtuin pathway activation, and cellular energy transfer mechanisms. Supplied at 1000mg.

Research Focus: Redox metabolism · Sirtuin pathway activation · Cellular energy homeostasis

For research use only. Not for human consumption.

Quantity

1000mg

Purity

996.18mg quantitative

Format

Lyophilised Powder

Testing

HPLC (Janoshik)

£299.99

20 in stock

Batch Verified
Third-Party Tested
COA Available Per Batch

Product Description

Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme found in all living cells that serves as a critical electron carrier in mitochondrial oxidative phosphorylation and glycolysis. It functions as both a substrate and coenzyme in metabolic redox reactions, cycling between its oxidized (NAD+) and reduced (NADH) forms. In laboratory research environments, NAD+ is studied for its role as a co-substrate for sirtuin deacetylases (SIRT1-7), poly(ADP-ribose) polymerases (PARPs), and cyclic ADP-ribose synthases (CD38/CD157). These enzyme families are central to DNA repair signaling, chromatin remodeling, calcium signaling, and metabolic regulation pathways under investigation in preclinical models. Experimental research has examined NAD+ bioavailability dynamics, biosynthetic pathway regulation (de novo, Preiss-Handler, and salvage pathways), and age-associated decline in cellular NAD+ levels using in-vitro and in-vivo experimental systems. Molecular Formula: C₂₁H₂₇N₇O₁₄P₂ Molecular Weight: 663.43 g/mol CAS: 53-84-9 This product is supplied at 1000mg for laboratory research applications. Not for human consumption.

Mechanism of Action

An essential coenzyme for redox reactions and a cosubstrate for sirtuins and PARPs. Cellular NAD+ declines with age; supplementation supports mitochondrial function, DNA repair, and epigenetic regulation through sirtuin activation.

Research Applications

Aging biology research; mitochondrial function studies; sirtuin pathway modulation; metabolic dysfunction models

Relevant Studies

1. Verdin (2015) Science 350(6265):1208-1213
PMID: 26785480 | View Publication
Landmark review of NAD+ biology in aging, demonstrating how declining NAD+ levels drive age-related metabolic and neurodegenerative disease.

2. Yoshino et al. (2011) Cell Metab 14(4):528-536
PMID: 21982712 | View Publication
Showed NMN (NAD+ precursor) restores NAD+ levels and treats pathophysiology of diet- and age-induced diabetes in mice through sirtuin activation.

Product Specifications

Specification

Details

Peptide

Nicotinamide Adenine Dinucleotide, Lyophilised

Quantity

1000mg

Purity

996.18mg quantitative

Testing

HPLC (Janoshik)

Storage

Room temperature, dry, protect from light

Certificate of Analysis

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Trust & Scarcity

Limited Batch

only 50 vials available

Discreet Shipping

Next-day delivery available

Purity Guarantee

≥99% lab-tested purity

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Research-grade compounds Independently batch tested COA available per batch
Third-Party Tested
≥99% Purity Verified
COA Available Per Batch

Research Enquiries

For enquiries relating to compound availability, batch data, or technical documentation, please contact: info@revivaxlabs.com